Sophora Japonica Extract

What is Sophora Japonica Extract?

Dried flowers and buds of Sophora Japonica extract (Huaihua) are a medicinal herb, Japan and Korea to treat hemorrhoids and hematemesis. Main components of Sophora Japonica extract powder include flavones, tetraglycosides, isoflavones, isoflavone tetraglycosides, triterpene glycosides, phospholipids, alkaloids, amino acids and polysaccharides [2]. Moreover, Sophora japonica contains five main flavonoids of rutin, quercetin, isorhamnetin, isorhamnetin, genistein and kaempferol.

Basic Information:

Sophora Japonica Extract Benefits:

1. Boosts Heart Health

When it comes to your heart health, recent research suggests that rutin can help maintain blood vessel elasticity, reduce blood vessel brittleness, lower capillary permeability and prevent complications caused by hypertension.

A 2018 animal study published in Experimental and Therapeutic Medicine found that it inhibits heart disease through signaling a specific protein kinases called ERK1/2 and Akt. The most effective Sophora Japonica extract dose used on pigs with coronary heart disease was 45 milligrams per kilogram of body weight. Rutin administration worked to reduce the size of dead tissue in the heart of pigs with heart disease, inhibited urine protein concentration and improved blood circulation.

2. Relieves Arthritis Symptoms

Animal studies show that this antioxidant has the power to inhibit acute and chronic inflammation. That makes it a potential natural treatment for arthritis. Researchers in Russia found that Sophora Japonica extract was able to reduce the overproduction of free radicals in rheumatoid arthritis. They concluded it can be considered a useful supporting pharmaceutical agent.

3. Fights Cancer

Rutin may serve as a therapeutic agent for fighting cancer because of its antioxidant and anti-inflammatory effects. It also has been shown to induce apoptosis, or cancer cell death, and display anti-tumor effects. Flavonoids have been used to sensitize cancer cells to anticancer drugs and reverse drug resistance for patients undergoing cancer treatment.

4. Protects Against Metabolic Disease

Research shows that rutin may protect us from developing metabolic syndrome as we age. Studies involving aged rats found that the flavonoid inhibited the increase of fasting blood glucose, insulin levels and blood pressure.

Rutin administration improved aging-related metabolic dysfunction in rats by reducing inflammation, lipid accumulation, oxidative stress and mitochondrial disease, a disorder that’s caused by failure of the mitochondria that’s found in almost every single cell of the human body.

5. Protects Brain Health

Research suggests that rutin has protective effects against brain injury and age-related damage. It also helps promote brain health because of its anti-inflammatory and antioxidant properties.

In 2018, research published in Oxidative Medicine and Cellular Longevity suggests that this bioflavonoid serves as a promising neuroprotective compound for the treatment of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and Huntington’s disease. Researchers believe that it protects brain health by reducing pro-inflammatory cytokines, improving antioxidant enzyme activities and restoring the activities of mitochondrial complex enzymes within our cells.

6. Prevents Blood Clots

Investigators at Harvard-affiliated Beth Israel Deaconess Medical Center found that rutin may serve as a novel strategy for preventing thrombosis in animal models. Thrombosis is when a blood clot forms in an artery or vein. Deep vein thrombosis is particularly dangerous because it can cause life-threatening complications, such as strokes and heart attacks.

7. Improves Circulation

In traditional medicine, rutin is known for its ability to strengthen blood vessels and improve circulation. It is used to reduce the appearance of varicose veins, relieve hemorrhoids and prevent hemorrhagic strokes that are caused by broken veins or arteries.

Sophora Japonica Extract Application:

Rutin is a naturally occurring substance found in fruit. It is readily available over-the-counter, as well. Although it is commonly used for human consumption, Rutin is used to treat certain conditions in dogs.

Rutin powder is used to lower cholesterol levels in dogs. According to the Veterinary Institute of Integrated Medicine, Rutin is the only recommended oral treatment for idiopathic chlyothorax in dogs.

Where to buy Sophora Japonica Extract?

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