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Rhizoma Coptidis Extract

Product Name:Rhizoma Coptidis Extract
Latin Name: Phellodendri Chinensis Cortex
Specification Ratio: berberine hydrochloride 97%
Part Used: bark
Appearance: Brown Yellow Powder
Test Method: TLC /titration
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What is Rhizoma Coptidis Extract?

Rhizoma coptidis extract is a commonly used traditional Chinese medicine that comes from the dried rhizome of Ranunculaceous plants. Although Coptidis rhizoma is frequently used for its numerous therapeutic properties, no comprehensive reports of antiviral activity against respiratory syncytial virus (RSV) exist. Coptidis Rhizoma extract (CRE)’s effectiveness against RSV in the human respiratory tract cell line (HEp2) and BALB/c mice was the subject of this investigation.

In HEp2 cells, an effective dose of coptidis combination extract significantly reduces RSV replication and RSV-induced cell death. Through the induction of type I interferon-related signaling and the antiviral state in HEp2 cells, this antiviral activity against RSV was achieved. More importantly, in BALB/c mice, oral administration of coptidis rhizoma extract protected them from RSV. We identified several compounds in the aqueous fraction through HPLC analysis, including; We established a connection between the immune modulation effect and palmatine’s antiviral properties.


Basic Information:

Product Name

Rhizoma Coptidis Extract

Latin Name

Phellodendron amurense Rupr.

Part Used



Yellow Needle Crystal Powder




Store in a well-closed container away from moisture and direct sunlight

Shelf Life

24 months if sealed and stored properly

Sterilization Method

High-temperature, non-irradiated.


Rhizoma Coptidis Extract Uses

Rhizoma coptidis extract, an isoquinoline alkaloid found in Berberis vulgaris and Coptis Chinensis, traditional medicinal plants, has been thought to be effective for treating obesity, hypertension, type-2 diabetes, hyperlipidemia, and gout in both animals and humans. Due to its strong biological and pharmacological properties, including antioxidative, anti-inflammatory, antidiarrheal, analgesic, antimicrobial, anticancer, hepatoprotective, and lipid- and glucose-lowering properties, it currently has some applications in fish nutrition and health.

Rhizoma coptidis extract in various fish diets has been shown to reduce liver pathological changes, intestinal histological and microbiota changes caused by high-lipid and high-carbohydrate diets, as well as boost fish growth performance, immune status, and stress resistance. Berberine’s beneficial effects, on the other hand, differ depending on the fish species, the base diet, the feeding method, the level of supplementation, and other factors.

Coptidis rhizoma extract’s bioavailability and toxicity, as well as its mechanisms in lipid and glucose metabolism, antioxidation, anti-inflammatory, and intestinal health protection, are highlighted in this review, along with other findings on berberine supplementation in fish diets. In addition, future perspectives on the use of berberine in fish nutrition and health are provided in this review.

[Usage and Dosage] 15-30g for horses and cattle; 25-45g coptidis combination extract for camels; 5-10g for sheep and pigs; 0.5-1g for rabbits and poultry. Appropriate amount for external use.

2~5g per 1kg body weight of fish, mixed with bait and fed; 1.5~2g per 1m3 water body, splashed into the fish pond.


[Identification] Take 2g of the powder of this product, add 20ml of chloroform, ultrasonicate for 30 minutes, filter, and treat the filter residue twice in the same way, combine the filtrate, recover the solvent under reduced pressure to dryness, add 1ml of chloroform to dissolve, and serve as Test solution. Take another 0.5 g of Evodia rutaecarpa as reference drug, and make a solution of reference drug in the same way. Then take limonin reference substance, add chloroform to make a solution containing 1mg per 1ml, as the reference substance solution. 

According to the thin-layer chromatography (general rule 0502) test, draw 6 μl of the test solution, 3 μl of the reference medicinal material solution and 2 μl of the reference solution, respectively spot on the same high-efficiency silica gel G thin-layer plate, and use petroleum ether (60 ~ 90 ℃) – Chloroform-acetone-methanol-diethylamine (5:2:2:1:0.2) as developer, pre-saturated for 30 minutes, developed, taken out, dried, sprayed with 2% vanillin sulfuric acid solution, at 105°C Heat until the spots are clearly colored. In the chromatogram of the test product, at the position corresponding to the chromatogram of the control medicinal material, the main spot of the same color appears; at the position corresponding to the chromatogram of the reference product, the spot of the same color appears.

The Best Rhizoma Coptidis Extract Supplier

Undersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.

We also focus on value-added services. We are available for service questions and information to support your business.

Why Choose Rhizoma Coptidis Extract?

Undersun specialize in coptidis rhizoma extract for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

Where to buy Rhizoma Coptidis Extract?

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Why choose us?

  • We believe that by offering high-quality products at affordable prices, we can make a difference in the lives of animals and their owners.
  • In the past development process, we insist on advancing with the times, the concept is constantly innovated, and the product structure is constantly adjusted.
  • Our experienced team is dedicated to providing quality products and services, ensuring our customers receive the support they need.
  • After years of development, we always insist on going all out to provide customers with high-quality products.
  • We take a holistic approach to animal care, recognizing the interconnectedness of physical, emotional, and mental health.
  • We have established long-term and stable cooperative relationships with a large number of well-known enterprises and are constantly strengthening our investment in technology and scientific research.
  • We are always looking for ways to improve our products and services, and we welcome feedback from our customers.
  • With our creative design team, years of accumulated production experience and strict quality concept, our company constantly develops Rhizoma Coptidis Extract that consumers like to apply.
  • We are always looking for ways to improve our sustainability, and we take our responsibility to the environment seriously.
  • We constantly improve the production technology level of the enterprise, actively develop and introduce new technologies, new equipment, and increase the investment in science and technology.

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